HMM Summary Page: TIGR02517

Functiontype II secretion system protein D
Gene SymbolgspD
Trusted Cutoff351.35
Domain Trusted Cutoff351.35
Noise Cutoff231.85
Domain Noise Cutoff231.85
Isology Typeequivalog
HMM Length600
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0008565: protein transporter activity molecular_function
GO:0015627: type II protein secretion system complex cellular_component
GO:0015628: protein secretion by the type II secretion system biological_process
AuthorHaft DH
Entry DateMar 9 2005 5:15PM
Last ModifiedFeb 17 2012 10:32AM
CommentIn Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See PMID:12654803). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516).
ReferencesRN [1] RM 12654803 RT Novel virulence-associated type II secretion system unique to high-pathogenicity Yersinia enterocolitica.
Genome PropertyGenProp0053: type II secretion (HMM)