| Accession | TIGR02515 |
| Name | IV_pilus_PilQ |
| Function | type IV pilus secretin PilQ |
| Gene Symbol | pilQ |
| Trusted Cutoff | 284.35 |
| Domain Trusted Cutoff | 284.35 |
| Noise Cutoff | 202.40 |
| Domain Noise Cutoff | 202.40 |
| Isology Type | subfamily |
| HMM Length | 428 |
| Mainrole Category | Cell envelope |
| Subrole Category | Surface structures |
| Gene Ontology Term | GO:0009297: pilus assembly biological_process |
| | GO:0009306: protein secretion biological_process |
| Author | Haft DH |
| Entry Date | Mar 9 2005 4:16PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. |
| References | DR PFAM; PF07660; STN
DR PFAM; PF03958; Secretin_N
DR PFAM; PF00263; Secretin_C
RN [1]
RM 14729699
RT A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds.
RA Chen CJ, Tobiason DM, Thomas CE, Shafer WM, Seifert HS, Sparling PF.
RL J Bacteriol. 2004 Feb;186(3):730-9. |
