HMM Summary Page: TIGR02513

Functiontype III secretion system chaperone, YscB family
Trusted Cutoff90.05
Domain Trusted Cutoff90.05
Noise Cutoff89.70
Domain Noise Cutoff89.70
Isology Typeequivalog
HMM Length140
AuthorHaft DH
Entry DateMar 8 2005 4:59PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family include YscB of Yersinia and functionally equivalent (but differently named) proteins from type III secretion systems of other pathogens that affect animal cells. YscB acts, along with SycN (TIGR02503), as a chaperone for YopN, a key part of a complex that regulates type III secretion so it responds to contact with the eukaryotic target cell.
ReferencesRN [1] RM 15701523 RT Three-dimensional structure of a macromolecular assembly that regulates type III secretion in Yersinia pestis. RA Schubot FD, Jackson MW, Penrose KJ, Cherry S, Tropea JE, Plano GV, Waugh DS. RL J Mol Biol. 2005 Mar 4;346(4):1147-61.
Genome PropertyGenProp0052: type III secretion (HMM)