| Accession | TIGR02512 |
| Name | FeFe_hydrog_A |
| Function | [FeFe] hydrogenase, group A |
| Trusted Cutoff | 405.95 |
| Domain Trusted Cutoff | 405.95 |
| Noise Cutoff | 300.65 |
| Domain Noise Cutoff | 300.65 |
| Isology Type | subfamily |
| EC Number | 1.12.-.- |
| HMM Length | 375 |
| Author | Haft DH |
| Entry Date | Mar 8 2005 4:26PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than Pfam model PF02906. This family represents a division among families that belong to PF02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length. |
| References | DR PFAM; PF02906; Fe_hyd_lg_C
RN [1]
RM 11070057
RT Iron hydrogenases and the evolution of anaerobic eukaryotes.
RA Horner DS, Foster PG, Embley TM.
RL Mol Biol Evol. 2000 Nov;17(11):1695-709.
RN [2]
RM PMID:20395274
RT The surprising diversity of clostridial hydrogenases: a comparative genomic perspective.
RA Calusinska M, Happe T, Joris B, Wilmotte A
RL Microbiology. 2010 Jun;156(Pt 6):1575-88. |
| Genome Property | GenProp0914: hydrogenase, [FeFe]-dependent (HMM) |
