HMM Summary Page: TIGR02507

Functiontetrahydromethanopterin S-methyltransferase, F subunit
Gene SymbolmtrF
Trusted Cutoff25.00
Domain Trusted Cutoff25.00
Noise Cutoff22.00
Domain Noise Cutoff22.00
Isology Typeequivalog_domain
EC Number2.1.1.86
HMM Length65
AuthorSelengut J
Entry DateMar 7 2005 1:54PM
Last ModifiedMay 10 2011 5:30PM
CommentThis small protein (MtrF) is one of eight subunits of the N5-methyltetrahydromethanopterin: coenzyme M methyltransferase in methanogenic archaea. This methyltranferase is membrane-associated enzyme complex that uses methy-transfer reaction to drive sodium-ion pump. Archaea domain, have evolved energy-yielding pathways marked by one-carbon biochemistry featuring novel cofactors and enzymes. This transferase is involved in the transfer of 'methyl' group from N5-methyltetrahydromethanopterin to coenzyme M. In an accompanying reaction, methane is produced by two-electron reduction of the methyl moiety in methyl-coenzyme M by another enzyme methyl-coenzyme M reductase.
ReferencesDR HAMAP; MF_01099; 6 of 7
Genome PropertyGenProp0288: tetrahydromethanopterin S-methyltransferase complex (HMM)
GenProp0722: methanogenesis marker set (HMM)