HMM Summary Page: TIGR02483

Trusted Cutoff430.55
Domain Trusted Cutoff430.55
Noise Cutoff373.85
Domain Noise Cutoff373.85
Isology Typesubfamily
HMM Length325
Mainrole CategoryEnergy metabolism
Subrole CategoryGlycolysis/gluconeogenesis
Gene Ontology TermGO:0006096: glycolysis biological_process
GO:0016773: phosphotransferase activity, alcohol group as acceptor molecular_function
AuthorRosovitz MJ, Haft DH
Entry DateFeb 23 2005 2:48PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC rather than ATP (EC The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal.
ReferencesRN [1] RM 9055413 RT Identification of ATP-dependent phosphofructokinase as a regulatory step in the glycolytic pathway of the actinomycete Streptomyces coelicolor A3(2). RA Alves AM, Euverink GJ, Bibb MJ, Dijkhuizen L. RL Appl Environ Microbiol. RN [2] RM 8550409 RT Characterization and phylogeny of the pfp gene of Amycolatopsis methanolica encoding PPi-dependent phosphofructokinase. RA Alves AM, Meijer W RL J Bacteriol. 1996 Jan;178(1):149-55. RN [3] RM 9555897 RT PPi-dependent phosphofructokinase from Thermoproteus tenax, an archaeal descendant of an ancient line in phosphofructokinase evolution. RA Siebers B, Klenk HP, Hensel R. RL J Bacteriol. 1998 Apr;180(8):2137-43. DR HAMAP; MF_00339; 14 of 182