HMM Summary Page: TIGR02470

Functionsucrose synthase
Trusted Cutoff810.40
Domain Trusted Cutoff810.40
Noise Cutoff348.60
Domain Noise Cutoff348.60
Isology Typeequivalog
EC Number2.4.1.13
HMM Length784
Mainrole CategoryEnergy metabolism
Subrole CategoryBiosynthesis and degradation of polysaccharides
Gene Ontology TermGO:0005985: sucrose metabolic process biological_process
GO:0016157: sucrose synthase activity molecular_function
AuthorHaft DH
Entry DateFeb 10 2005 1:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents sucrose synthase, an enzyme that, despite its name, generally uses rather produces sucrose. Sucrose plus UDP (or ADP) becomes D-fructose plus UDP-glucose (or ADP-glucose), which is then available for cell wall (or starch) biosynthesis. The enzyme is homologous to sucrose phosphate synthase, which catalyzes the penultimate step in sucrose synthesis. Sucrose synthase is found, so far, exclusively in plants and cyanobacteria.
ReferencesRN [1] RM 11950997 RT Evolution of sucrose synthesis. RA Lunn JE. RL Plant Physiol. 2002 Apr;128(4):1490-500. RN [2] RM 12062401 RT Sucrose metabolism: Anabaena sucrose-phosphate synthase and sucrose-phosphate phosphatase define minimal functional domains shuffled during evolution. RA Cumino A, Curatti L, Giarrocco L, Salerno GL. RL FEBS Lett. 2002 Apr 24;517(1-3):19-23. DR EXPERIMENTAL; GB|CAA09297.1; Anabaena sp. PCC 7119