HMM Summary Page: TIGR02467

Functionprecorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit
Gene SymbolcbiE
Trusted Cutoff92.90
Domain Trusted Cutoff92.90
Noise Cutoff84.60
Domain Noise Cutoff84.60
Isology Typeequivalog_domain
EC Number2.1.1.132
HMM Length204
Gene Ontology TermGO:0046025: precorrin-6Y C5,15-methyltransferase (decarboxylating) activity molecular_function
GO:0046140: corrin biosynthetic process biological_process
AuthorSelengut J
Entry DateFeb 9 2005 1:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model recognizes the CbiE methylase which is responsible, in part (along with CbiT), for methylating precorrin-6y (or cobalt-precorrin-6y) at both the 5 and 15 positions as well as the concomitant decarbozylation at C-12. In many organisms, this protein is fused to the CbiT subunit. The fused protein, when found in organisms catalyzing the oxidative version of the cobalamin biosynthesis pathway, is called CobL.
Genome PropertyGenProp0113: cobyrinic acid diamide biosynthesis, aerobic pathway (HMM)
GenProp0275: cobyrinic acid diamide biosynthesis, anaerobic pathway (HMM)