HMM Summary Page: TIGR02463

Functionmannosyl-3-phosphoglycerate phosphatase homolog
Trusted Cutoff282.00
Domain Trusted Cutoff282.00
Noise Cutoff184.75
Domain Noise Cutoff184.75
Isology Typehypoth_equivalog
EC Number3.1.3.-
HMM Length216
Mainrole CategoryUnknown function
Subrole CategoryGeneral
Gene Ontology TermGO:0016791: phosphatase activity molecular_function
AuthorHaft DH
Entry DateFeb 4 2005 4:27PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of members of the HAD superfamily, subfamily IIB. All members are closely related to mannosyl-3-phosphoglycerate phosphatase, the second enzyme in a two-step pathway for biosynthesis of mannosylglycerate, a compatible solute present in some thermophiles and in Dehalococcoides ethenogenes. However, members of this family are separable in a neighbor-joining tree constructed from a multiple sequence alignment and are found only in mesophiles that lack the companion mannosyl-3-phosphoglycerate synthase (TIGR02460). Members of this family are like to act on a compound related to yet distinct from mannosyl-3-phosphoglycerate.
References DR HAMAP; MF_00617; 14 of 19