HMM Summary Page: TIGR02461

Functionmannosyl-3-phosphoglycerate phosphatase
Gene SymbolmpgP
Trusted Cutoff244.35
Domain Trusted Cutoff244.35
Noise Cutoff176.50
Domain Noise Cutoff176.50
Isology Typeequivalog
EC Number3.1.3.70
HMM Length227
Gene Ontology TermGO:0050531: mannosyl-3-phosphoglycerate phosphatase activity molecular_function
AuthorHaft DH
Entry DateFeb 4 2005 10:52AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are mannosyl-3-phosphoglycerate phosphatase (EC It acts sequentially after mannosyl-3-phosphoglycerate synthase (EC in a two-step pathway of biosynthesis of the compatible solute mannosylglycerate, a typical osmolyte of thermophiles.
ReferencesRN [1] RM 11562374 RT Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii. Biochemical and genetic characterization of key enzymes. RA Empadinhas N, Marugg JD, Borges N, Santos H, da Costa MS. RL J Biol Chem. 2001 Nov 23;276(47):43580-8. DR HAMAP; MF_00617; 4 of 19
Genome PropertyGenProp0281: mannosylglycerate biosynthesis (HMM)