HMM Summary Page: TIGR02460

Functionmannosyl-3-phosphoglycerate synthase
Gene SymbolmpgS
Trusted Cutoff351.20
Domain Trusted Cutoff351.20
Noise Cutoff132.00
Domain Noise Cutoff132.00
Isology Typeequivalog
EC Number2.4.1.217
HMM Length383
Gene Ontology TermGO:0050504: mannosyl-3-phosphoglycerate synthase activity molecular_function
AuthorHaft DH
Entry DateFeb 4 2005 10:37AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of examples of mannosyl-3-phosphoglycerate synthase (MPGS), which together mannosyl-3-phosphoglycerate phosphatase (MPGP) comprises a two-step pathway for mannosylglycerate biosynthesis. Mannosylglycerate is a compatible solute that tends to be restricted to extreme thermophiles of archaea and bacteria. Note that in Rhodothermus marinus, this pathway is one of two; the other is condensation of GDP-mannose with D-glycerate by mannosylglycerate synthase.
ReferencesRN [1] RM 12788726 RT The bacterium Thermus thermophilus, like hyperthermophilic archaea, uses a two-step pathway for the synthesis of mannosylglycerate. RA Empadinhas N, Albuquerque L, Henne A, Santos H, da Costa MS. RL Appl Environ Microbiol. 2003 Jun;69(6):3272-9.
Genome PropertyGenProp0281: mannosylglycerate biosynthesis (HMM)