HMM Summary Page: TIGR02446

Functionacetyl-CoA C-acyltransferase FadI
Gene SymbolfadI
Trusted Cutoff711.55
Domain Trusted Cutoff711.55
Noise Cutoff428.10
Domain Noise Cutoff428.10
Isology Typeequivalog
EC Number2.3.1.16
HMM Length430
Mainrole CategoryFatty acid and phospholipid metabolism
Subrole CategoryDegradation
Gene Ontology TermGO:0003988: acetyl-CoA C-acyltransferase activity molecular_function
GO:0009062: fatty acid catabolic process biological_process
AuthorRosovitz MJ, Haft DH
Entry DateJan 31 2005 2:43PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis subunit of the FadJI complex has acetyl-CoA C-acyltransferase (EC activity, and is also known as beta-ketothiolase and fatty oxidation complex, beta subunit, and YfcY. This protein is almost always located adjacent to FadJ (TIGR02440). The FadJI complex is needed for anaerobic beta-oxidation of short-chain fatty acids in E. coli.
ReferencesRN [1] RM 12535077 RT A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic beta-oxidation pathway. RA Campbell JW, Morgan-Kiss RM, Cronan JE Jr. RL Mol Microbiol. 2003 Feb;47(3):793-805. DR HAMAP; MF_01618; 61 of 63