Accession | TIGR02437 |
Name | FadB |
Function | fatty oxidation complex, alpha subunit FadB |
Gene Symbol | fadB |
Trusted Cutoff | 933.55 |
Domain Trusted Cutoff | 933.55 |
Noise Cutoff | 726.70 |
Domain Noise Cutoff | 726.70 |
Isology Type | equivalog |
EC Number | 4.2.1.17 5.3.3.8 1.1.1.35 5.1.2.3 |
HMM Length | 714 |
Mainrole Category | Fatty acid and phospholipid metabolism |
Subrole Category | Degradation |
Gene Ontology Term | GO:0003857: 3-hydroxyacyl-CoA dehydrogenase activity molecular_function |
| GO:0004165: dodecenoyl-CoA delta-isomerase activity molecular_function |
| GO:0004300: enoyl-CoA hydratase activity molecular_function |
| GO:0008692: 3-hydroxybutyryl-CoA epimerase activity molecular_function |
| GO:0009062: fatty acid catabolic process biological_process |
Author | Rosovitz MJ, Haft DH |
Entry Date | Jan 25 2005 3:23PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members represent alpha subunit of multifunctional enzyme complex of the fatty acid degradation cycle. Activities include: enoyl-CoA hydratase (EC 4.2.1.17), dodecenoyl-CoA delta-isomerase activity (EC 5.3.3.8), 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35), 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3). A representative is E. coli FadB (SP:P21177). This model excludes the FadJ family represented by SP:P77399. |
References | RN [1]
RM 1699931
RT Primary sequence of the Escherichia coli fadBA operon, encoding the fatty acid-oxidizing multienzyme complex, indicates a high degree of homology to eucaryotic enzymes.
RA DiRusso CC.
RL J Bacteriol. 1990 Nov;172(11):6459-68.
DR HAMAP; MF_01621; 78 of 80 |