HMM Summary Page: TIGR02431

Functionbeta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family
Trusted Cutoff284.75
Domain Trusted Cutoff284.75
Noise Cutoff219.60
Domain Noise Cutoff219.60
Isology Typesubfamily
HMM Length248
Mainrole CategoryRegulatory functions
Subrole CategoryDNA interactions
AuthorHaft DH
Entry DateJan 14 2005 5:30PM
Last ModifiedFeb 14 2011 3:27PM
CommentMember of this family are IclR-type transcriptional regulators with similar DNA binding sites, able to bind at least three different metabolites related to protocatechuate metabolism. Beta-ketoadipate is the inducer for PcaR, p-hydroxybenzoate for PobR, and protocatechuate for PcaU.
ReferencesDR PFAM; PF01614; IclR
Genome PropertyGenProp0273: protocatechuate degradation to beta-ketoadipate (HMM)