HMM Summary Page: TIGR02425

Function4-carboxymuconolactone decarboxylase
Gene SymbolpcaC
Trusted Cutoff155.70
Domain Trusted Cutoff155.70
Noise Cutoff138.10
Domain Noise Cutoff138.10
Isology Typeequivalog
EC Number4.1.1.44
HMM Length123
Mainrole CategoryEnergy metabolism
Subrole CategoryOther
Gene Ontology TermGO:0047575: 4-carboxymuconolactone decarboxylase activity molecular_function
AuthorHaft DH
Entry DateJan 11 2005 1:16PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are 4-carboxymuconolactone decarboxylase, which catalyzes the third step in the catabolism of protocatechuate (and therefore the fourth step in the catabolism of para-hydroxybenzoate, of 3-hydroxybenzoate, of vanillate, etc.). Most members of this family are encoded within protocatechuate catabolism operons. This protein is sometimes found as a fusion protein with other enzymes of the pathway, as in Rhodococcus opacus, Streptomyces avermitilis, and Caulobacter crescentus.
ReferencesRN [1] RM 15006791 RT Diverse organization of genes of the beta-ketoadipate pathway in members of the marine Roseobacter lineage. RA Buchan A, Neidle EL, Moran MA. RL Appl Environ Microbiol. 2004 Mar;70(3):1658-68.
Genome PropertyGenProp0273: protocatechuate degradation to beta-ketoadipate (HMM)