HMM Summary Page: TIGR02412
| Accession | TIGR02412 |
| Name | pepN_strep_liv |
| Function | aminopeptidase N |
| Gene Symbol | pepN |
| Trusted Cutoff | 591.20 |
| Domain Trusted Cutoff | 591.20 |
| Noise Cutoff | 412.75 |
| Domain Noise Cutoff | 412.75 |
| Isology Type | equivalog |
| EC Number | 3.4.11.2 |
| HMM Length | 832 |
| Author | Haft DH |
| Entry Date | Dec 22 2004 4:28PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family is a subset of the members of the zinc metallopeptidase family M1 (PF01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site). |
| References | RM 7909302 RT The aminopeptidase N-encoding pepN gene of Streptomyces lividans 66. RA Butler MJ, Aphale JS, Binnie C, DiZonno MA, Krygsman P, Soltes GA, Walczyk E, Malek LT. RL Gene. 1994 Apr 8;141(1):115-9. |