HMM Summary Page: TIGR02410

Functiontrimethyllysine dioxygenase
Trusted Cutoff268.30
Domain Trusted Cutoff268.30
Noise Cutoff232.85
Domain Noise Cutoff232.85
Isology Typeequivalog
EC Number1.14.11.8
HMM Length362
AuthorHaft DH
Entry DateDec 22 2004 12:53PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family with known function act as trimethyllysine dioxygenase, an enzyme in the pathway for carnitine biosynthesis from lysine. This enzyme is homologous to gamma-butyrobetaine,2-oxoglutarate dioxygenase, which catalyzes the last step in carnitine biosynthesis. Members of this family appear to be eukaryotic only.