HMM Summary Page: TIGR02409

Functiongamma-butyrobetaine hydroxylase
Trusted Cutoff414.75
Domain Trusted Cutoff414.75
Noise Cutoff316.65
Domain Noise Cutoff316.65
Isology Typeequivalog
EC Number1.14.11.1
HMM Length366
AuthorHaft DH
Entry DateDec 22 2004 12:01PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are gamma-butyrobetaine hydroxylase, both bacterial and eukarytotic. This enzyme catalyzes the last step in the conversion of lysine to carnitine. Carnitine can serve as a compatible solvent in bacteria and also participates in fatty acid metabolism.
ReferencesDR PFAM; PF03322; Gamma-butyrobetaine hydroxylase RM 8504802 RT gamma-Butyrobetaine hydroxylase. Structural characterization of the Pseudomonas enzyme. RA Ruetschi U, Nordin I, Odelhog B, Jornvall H, Lindstedt S. RL Eur J Biochem. 1993 May 1;213(3):1075-80.