HMM Summary Page: TIGR02407

Functiondiaminobutyrate--2-oxoglutarate aminotransferase
Gene SymbolectB
Trusted Cutoff552.20
Domain Trusted Cutoff552.20
Noise Cutoff407.45
Domain Noise Cutoff407.45
Isology Typeequivalog
EC Number2.6.1.76
HMM Length412
Mainrole CategoryCellular processes
Subrole CategoryAdaptations to atypical conditions
Gene Ontology TermGO:0045303: diaminobutyrate-2-oxoglutarate transaminase activity molecular_function
AuthorHaft DH
Entry DateDec 20 2004 11:16AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family of class III pyridoxal-phosphate-dependent aminotransferases are diaminobutyrate--2-oxoglutarate aminotransferase (EC that catalyze the first step in ectoine biosynthesis from L-aspartate beta-semialdehyde. This family is readily separated phylogenetically from enzymes with the same substrate and product but involved in other process such as siderophore (SP|Q9Z3R2) or 1,3-diaminopropane (SP|P44951) biosynthesis. The family TIGR00709 previously included both groups but has now been revised to exclude the ectoine biosynthesis proteins of this family. Ectoine is a compatible solute particularly effective in conferring salt tolerance.
ReferencesDR PFAM; PF00202; aminotransferase, class III
Genome PropertyGenProp0268: ectoine biosynthesis (HMM)