HMM Summary Page: TIGR02401

Functionmalto-oligosyltrehalose synthase
Gene SymboltreY
Trusted Cutoff498.65
Domain Trusted Cutoff498.65
Noise Cutoff380.65
Domain Noise Cutoff380.65
Isology Typeequivalog
EC Number5.4.99.15
HMM Length838
Mainrole CategoryEnergy metabolism
Subrole CategoryBiosynthesis and degradation of polysaccharides
Gene Ontology TermGO:0005992: trehalose biosynthetic process biological_process
GO:0047470: (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity molecular_function
AuthorHaft DH
Entry DateDec 16 2004 2:43PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme, formally named (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase, is the TreY enzyme of the TreYZ pathway of trehalose biosynthesis, an alternative to the OtsAB pathway. Trehalose may be incorporated into more complex compounds but is best known as compatible solute. It is one of the most effective osmoprotectants, and unlike the various betaines does not require nitrogen for its synthesis.
ReferencesRM 8611744 RT Purification and properties of a novel enzyme, maltooligosyl trehalose synthase, from Arthrobacter sp. Q36. RA Nakada T, Maruta K, Tsusaki K, Kubota M, Chaen H, Sugimoto T, Kurimoto M, Tsujisaka Y. RL Biosci Biotechnol Biochem. 1995 Dec;59(12):2210-4.
Genome PropertyGenProp0266: trehalose biosynthesis, TreYZ pathway (HMM)