HMM Summary Page: TIGR02396

FunctionrpsU-divergently transcribed protein
Trusted Cutoff74.55
Domain Trusted Cutoff74.55
Noise Cutoff46.55
Domain Noise Cutoff46.55
Isology Typehypoth_equivalog
HMM Length186
Mainrole CategoryUnknown function
Subrole CategoryGeneral
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0008150: biological_process biological_process
AuthorHaft DH
Entry DateDec 9 2004 5:23PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis uncharacterized protein is found in a number of Alphaproteobacteria and, with N-terminal regions long enough to be transit peptides, in eukaryotes. This phylogeny suggests mitochondrial derivation. In several Alphaproteobacteria, the gene for this protein is encoded divergently from rpsU, the gene for ribosomal protein S21. S21 is unusual in being encoded outside the usual long ribosomal protein operons, but rather in contexts that suggest regulation of the initiation of protein translation.
ReferencesRN [1] RM 15229555 RT Analysis of genomic context: prediction of functional associations from conserved bidirectionally transcribed gene pairs. RA Korbel JO, Jensen LJ, von Mering C, Bork P. RL Nat Biotechnol. 2004 Jul;22(7):911-7.