HMM Summary Page: TIGR02392

Functionalternative sigma factor RpoH
Gene SymbolrpoH
Trusted Cutoff323.10
Domain Trusted Cutoff323.10
Noise Cutoff185.40
Domain Noise Cutoff185.40
Isology Typeequivalog
HMM Length270
Mainrole CategoryCellular processes
Subrole CategoryAdaptations to atypical conditions
Gene Ontology TermGO:0006352: transcription initiation, DNA-dependent biological_process
GO:0016987: sigma factor activity molecular_function
AuthorHaft DH
Entry DateDec 6 2004 2:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentA sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors.