| Accession | TIGR02384 |
| Name | RelB_DinJ |
| Function | addiction module antitoxin, RelB/DinJ family |
| Trusted Cutoff | 45.65 |
| Domain Trusted Cutoff | 45.65 |
| Noise Cutoff | 33.45 |
| Domain Noise Cutoff | 33.45 |
| Isology Type | subfamily |
| HMM Length | 85 |
| Mainrole Category | Cellular processes |
| Subrole Category | Toxin production and resistance |
| Author | Haft DH |
| Entry Date | Nov 30 2004 4:35PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than Pfam model PF04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. |
| Genome Property | GenProp0321: toxin-antitoxin system, type II (HMM) |
