HMM Summary Page: TIGR02373

Functionphotoactive yellow protein
Gene Symbolpyp
Trusted Cutoff143.05
Domain Trusted Cutoff143.05
Noise Cutoff41.70
Domain Noise Cutoff41.70
Isology Typeequivalog
HMM Length124
AuthorHaft DH
Entry DateNov 11 2004 8:35AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are photoactive yellow protein, a cytosolic, 14-kDa light-sensing protein which has a 4-hydroxycinnamyl (p-coumaric acid) chromophore covalently linked to a Cys residue. The enzyme 4-coumarate--CoA ligase as described by TIGR02372 is required for its biosynthesis. The modified Cys is in a PAS (PF00989) domain, frequently found in signal transducing proteins. Members are known in alpha and gamma Proteobacteria that include Rhodobacter capsulatus, Halorhodospira halophila, Rhodospirillum centenum, etc.
ReferencesDR PFAM; PF00989; PAS domain RM 7756254 RT 1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore. RA Borgstahl GE, Williams DR, Getzoff ED. RL Biochemistry. 1995 May 16;34(19):6278-87.