Accession | TIGR02354 |
Name | thiF_fam2 |
Function | thiamine biosynthesis protein ThiF |
Gene Symbol | thiF |
Trusted Cutoff | 152.20 |
Domain Trusted Cutoff | 152.20 |
Noise Cutoff | 114.60 |
Domain Noise Cutoff | 114.60 |
Isology Type | equivalog |
HMM Length | 200 |
Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
Subrole Category | Thiamine |
Gene Ontology Term | GO:0009228: thiamine biosynthetic process biological_process |
| GO:0016779: nucleotidyltransferase activity molecular_function |
Author | Haft DH |
Entry Date | Oct 13 2004 4:20PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of the HesA/MoeB/ThiF family of proteins (PF00899) include a number of members encoded in the midst of thiamine biosynthetic operons. This mix of known and putative ThiF proteins shows a deep split in phylogenetic trees, with one the E. coli ThiF and the E. coli MoeB proteins seemingly more closely related than E. coli ThiF and Campylobacter (for example) ThiF. This model represents the divergent clade of putative ThiF proteins such found in Campylobacter. |
References | DR PFAM; PF00899; ThiF/MoeB/HesA family |
Genome Property | GenProp0250: thiamine: hydroxyethylthiazole from 1-deoxy-D-xylulose-5-phosphate, cysteine, either Tyr or Gly (HMM) |