| Accession | TIGR02332 |
| Name | HpaX |
| Function | 4-hydroxyphenylacetate permease |
| Gene Symbol | hpaX |
| Trusted Cutoff | 615.40 |
| Domain Trusted Cutoff | 615.40 |
| Noise Cutoff | 527.90 |
| Domain Noise Cutoff | 527.90 |
| Isology Type | equivalog |
| HMM Length | 412 |
| Author | Selengut J, Haft DH |
| Entry Date | Oct 1 2004 9:44AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein is a part of the Major Facilitator Superfamily (Pfam family PF07690). Member of this family are found in a number of proteobacterial genomes, but only in the context of having genes for 4-hydroxyphenylacetate (4-HPA) degradation. The protein is characterized by Prieto, et al. (PMID:9315705) as 4-hydroxyphenylacetate permease in E. coli, where 3-HPA and 3,4-dihydroxyphenylacetate are shown to competitively inhibit 4-HPA transport and therefore also interact specificially. |
| References | RN [1]
RM 9315705
RT Identification of the 4-hydroxyphenylacetate transport gene of Escherichia coli W: construction of a highly sensitive cellular biosensor.
RA Prieto MA, Garcia JL.
RL FEBS Lett. 1997 Sep 8;414(2):293-7. |
| Genome Property | GenProp0231: 4-hydroxyphenylacetate degradation (HMM) |
