HMM Summary Page: TIGR02331

FunctionRib/alpha/Esp surface antigen repeat
Trusted Cutoff35.25
Domain Trusted Cutoff35.25
Noise Cutoff24.05
Domain Noise Cutoff24.05
Isology Typerepeat
HMM Length80
AuthorHaft DH
Entry DateSep 30 2004 2:52PM
Last ModifiedFeb 14 2011 3:27PM
CommentSequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.
ReferencesRN [1] RM 8702550 RT Identification of a family of streptococcal surface proteins with extremely repetitive structure. RA Wastfelt M, Stalhammar-Carlemalm M, Delisse AM, Cabezon T, Lindahl G. RL J Biol Chem. 1996 Aug 2;271(31):18892-7.