| Accession | TIGR02323 |
| Name | CP_lyasePhnK |
| Function | phosphonate C-P lyase system protein PhnK |
| Gene Symbol | phnK |
| Trusted Cutoff | 302.85 |
| Domain Trusted Cutoff | 302.85 |
| Noise Cutoff | 158.50 |
| Domain Noise Cutoff | 158.50 |
| Isology Type | equivalog |
| HMM Length | 239 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Phosphorus compounds |
| Gene Ontology Term | GO:0018835: carbon phosphorus lyase activity molecular_function |
| | GO:0019634: organic phosphonate metabolic process biological_process |
| Author | Haft DH, Selengut J |
| Entry Date | Sep 28 2004 1:02PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. |
| References | RN [1]
RM 8388873
RT Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation, using TnphoA' elements.
RA Metcalf WW, Wanner BL.
RL J Bacteriol. 1993 Jun;175(11):3430-42. |
| Genome Property | GenProp0232: phosphonates C-P lyase system (HMM) |
