HMM Summary Page: TIGR02319
| Accession | TIGR02319 |
| Name | CPEP_Pphonmut |
| Function | carboxyvinyl-carboxyphosphonate phosphorylmutase |
| Gene Symbol | bcpA |
| Trusted Cutoff | 420.05 |
| Domain Trusted Cutoff | 420.05 |
| Noise Cutoff | 255.20 |
| Domain Noise Cutoff | 255.20 |
| Isology Type | equivalog |
| EC Number | 2.7.8.23 |
| HMM Length | 294 |
| Author | Haft DH |
| Entry Date | Sep 27 2004 4:38PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family consists of carboxyvinyl-carboxyphosphonate phosphorylmutase (CPEP phosphonomutase), an unusual enzyme involved in the biosynthesis of the antibiotic bialaphos. So far, it is known only in that pathway and only in Streptomyces hygroscopicus. Some related proteins annotated as being functionally equivalent are likely misannotated examples of methylisocitrate lyase, an enzyme of priopionate utilization. |
| References | DR SWISSPROT; P11435; Streptomyces hygroscopicus RN [1] RM 2160937 RT Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation. RA Hidaka T, Imai S, Hara O, Anzai H, Murakami T, Nagaoka K, Seto H. RL J Bacteriol. 1990 Jun;172(6):3066-72. |