HMM Summary Page: TIGR02310

Function4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
Gene SymbolhpaB
Trusted Cutoff885.20
Domain Trusted Cutoff885.20
Noise Cutoff741.30
Domain Noise Cutoff741.30
Isology Typeequivalog
EC Number1.14.14.9
HMM Length519
AuthorSelengut J
Entry DateSep 23 2004 9:27AM
Last ModifiedMay 22 2012 12:18PM
CommentThis gene for this monooxygenase is found within apparent operons for the degradation of 4-hydroxyphenylacetic acid in Shigella, Photorhabdus and Pasteurella. The family modelled by this HMM is narrowly limited to gammaproteobacteria to exclude other aromatic hydroxylases involved in various secondary metabolic pathways. Generally, this enzyme acts with the assistance of a small flavin reductase domain protein (HpaC) to provide the cycle the flavin reductant for the reaction. This family of sequences is a member of a larger subfamily of monooxygenases (PF03241).
Genome PropertyGenProp0231: 4-hydroxyphenylacetate degradation (HMM)