HMM Summary Page: TIGR02308

FunctionRNA ligase, T4 RnlA family
Trusted Cutoff242.25
Domain Trusted Cutoff242.25
Noise Cutoff74.90
Domain Noise Cutoff74.90
Isology Typeequivalog
EC Number6.5.1.3
HMM Length373
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryProphage functions
AuthorHaft DH
Entry DateSep 22 2004 2:48PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are phage proteins with ATP-dependent RNA ligase activity. Host defense to phage may include cleavage and inactivation of specific tRNA molecules; members of this family act to reverse this RNA damage. The enzyme is adenylated, transiently, on a Lys residue in a motif KXDGSL.
ReferencesDR EXPERIMENTAL; SP|P00971; Bacteriophage T4