| Accession | TIGR02288 |
| Name | PaaN_2 |
| Function | phenylacetic acid degradation protein paaN |
| Gene Symbol | paaN |
| Trusted Cutoff | 578.75 |
| Domain Trusted Cutoff | 578.75 |
| Noise Cutoff | 271.80 |
| Domain Noise Cutoff | 271.80 |
| Isology Type | equivalog |
| HMM Length | 551 |
| Gene Ontology Term | GO:0010124: phenylacetate catabolic process biological_process |
| Author | Selengut J |
| Entry Date | Sep 2 2004 3:52PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme is proposed to act in the ring-opening step of phenylacetic acid degradation [1] which follows ligation of the acid with coenzyme A (by PaaF) and hydroxylation by a multicomponent non-heme iron hydroxylase complex (PaaGHIJK). Gene symbols have been standardized in [2]. This enzyme is related to aldehyde dehydrogenases and has a domain which is a member of the PF00171 family.
This family includes sequences from Burkholderia, Bordetella, Streptomyces. Other PaaN enzymes are represented by a separate model, TIGR02278. |
| References | RN [1]
RM PMID: 11260461
RT The phenylacetyl-CoA catabolon: a complex catabolic unit with broad biotechnological applications.
RA Luengo JM, Garcia JL, Olivera ER.
RL Mol Microbiol. 2001 Mar;39(6):1434-42.
RN [2]
RM PMID: 10766858
RT Transcriptional regulation of the divergent paa catabolic operons for phenylacetic acid degradation in Escherichia coli.
RA Ferrandez A, Garcia JL, Diaz E.
RL J Biol Chem. 2000 Apr 21;275(16):12214-22. |
| Genome Property | GenProp0210: phenylacetic acid catabolism (HMM) |
