HMM Summary Page: TIGR02282

Functionlytic murein transglycosylase B
Gene SymbolmltB
Trusted Cutoff281.40
Domain Trusted Cutoff281.40
Noise Cutoff222.40
Domain Noise Cutoff222.40
Isology Typeequivalog
EC Number2.4.-.-
HMM Length290
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of murein sacculus and peptidoglycan
Gene Ontology TermGO:0009253: peptidoglycan catabolic process biological_process
GO:0016757: transferase activity, transferring glycosyl groups molecular_function
AuthorHaft DH
Entry DateAug 31 2004 4:00PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of lytic murein transglycosylases (murein hydrolases) in the family of MltB, which is a membrane-bound lipoprotein in Escherichia coli. The N-terminal lipoprotein modification motif is conserved in about half the members of this family. The term Slt35 describes a naturally occurring soluble fragment of MltB. Members of this family never contain the putative peptidoglycan binding domain described by Pfam model PF01471, which is associated with several classes of bacterial cell wall lytic enzymes.
ReferencesDR EXPERIMENTAL; SP:P41052; Escherichia coli