| Accession | TIGR02279 |
| Name | PaaC-3OHAcCoADH |
| Function | 3-hydroxyacyl-CoA dehydrogenase PaaC |
| Gene Symbol | paaC |
| Trusted Cutoff | 669.40 |
| Domain Trusted Cutoff | 669.40 |
| Noise Cutoff | 593.65 |
| Domain Noise Cutoff | 593.65 |
| Isology Type | equivalog |
| EC Number | 1.1.1.- |
| HMM Length | 503 |
| Author | Selengut J |
| Entry Date | Aug 31 2004 12:56PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This 3-hydroxyacyl-CoA dehydrogenase is involved in the degradation of phenylacetic acid, presumably in steps following the opening of the phenyl ring [1]. The sequences included in this model are all found in aparrent operons with other related genes such as paaA, paaB, paaD, paaE, paaF and paaN [2]. Some genomes contain these other genes without an apparent paaC in the same operon - possibly in these cases a different dehydrogenase involved in fatty acid degradation may fill in the needed activity. This enzyme has domains which are members of the PF02737 and PF00725 families. |
| References | RN [1]
RM PMID: 9748275
RT Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway.
RA Ferrandez A, Minambres B, Garcia B, Olivera ER, Luengo JM, Garcia JL, Diaz E.
RL J Biol Chem. 1998 Oct 2;273(40):25974-86.
RN [2]
RM PMID: 11260461
RT The phenylacetyl-CoA catabolon: a complex catabolic unit with broad biotechnological applications.
RA Luengo JM, Garcia JL, Olivera ER.
RL Mol Microbiol. 2001 Mar;39(6):1434-42. |
| Genome Property | GenProp0210: phenylacetic acid catabolism (HMM) |
