HMM Summary Page: TIGR02275

Function(2,3-dihydroxybenzoyl)adenylate synthase
Trusted Cutoff723.55
Domain Trusted Cutoff723.55
Noise Cutoff373.45
Domain Noise Cutoff373.45
Isology Typeequivalog
EC Number2.7.7.58
HMM Length526
Mainrole CategoryTransport and binding proteins
Subrole CategoryCations and iron carrying compounds
Gene Ontology TermGO:0008668: (2,3-dihydroxybenzoyl)adenylate synthase activity molecular_function
GO:0019290: siderophore biosynthetic process biological_process
AuthorHaft DH
Entry DateAug 27 2004 4:00PM
Last ModifiedFeb 14 2011 3:27PM
CommentProteins in this family belong to the AMP-binding enzyme family (PF00501). Members activate 2,3-dihydroxybenzoate (DHB) by ligation of AMP from ATP with the release of pyrophosphate; many are involved in synthesis of siderophores such as enterobactin, vibriobactin, vulnibactin, etc. The most closely related proteine believed to differ in function activates salicylate rather than DHB.
ReferencesDR PFAM; PF00501; AMP-binding enzyme