| Accession | TIGR02235 |
| Name | menA_cyano-plnt |
| Function | 1,4-dihydroxy-2-naphthoate phytyltransferase |
| Gene Symbol | menA |
| Trusted Cutoff | 225.00 |
| Domain Trusted Cutoff | 225.00 |
| Noise Cutoff | 155.10 |
| Domain Noise Cutoff | 155.10 |
| Isology Type | equivalog |
| EC Number | 2.5.1.- |
| HMM Length | 285 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Menaquinone and ubiquinone |
| Gene Ontology Term | GO:0004659: prenyltransferase activity molecular_function |
| | GO:0042372: phylloquinone biosynthetic process biological_process |
| Author | Selengut J |
| Entry Date | Jul 6 2004 4:21PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family of phytyltransferases, found in plants and cyanobacteria, are involved in the biosythesis of phylloquinone (Vitamin K1). Phylloquinone is a critical component of photosystem I [1]. The closely related MenA enzyme from bacteria transfers a prenyl group (which only differs in the saturation of the isoprenyl groups) in the biosynthesis of menaquinone. Activity towards both substrates in certain organisms should be considered a possibility. |
| References | RN [1]
RM PMID: 3130097
RT Functional role of vitamin K in photosystem I of the cyanobacterium Synechocystis 6803.
RA Biggins J, Mathis P.
RL Biochemistry. 1988 Mar 8;27(5):1494-500. |
