HMM Summary Page: TIGR02227

Functionsignal peptidase I
Gene SymbollepB
Trusted Cutoff47.00
Domain Trusted Cutoff47.00
Noise Cutoff43.00
Domain Noise Cutoff43.00
Isology Typeequivalog
EC Number3.4.21.89
HMM Length162
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0006465: signal peptide processing biological_process
GO:0009004: signal peptidase I activity molecular_function
GO:0009306: protein secretion biological_process
AuthorHaft DH
Entry DateJun 21 2004 11:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes.
ReferencesDR PFAM; PF00461; Signal peptidase I
Genome PropertyGenProp0205: signal recognition system, bacterial (HMM)