HMM Summary Page: TIGR02225

Functiontyrosine recombinase XerD
Gene SymbolxerD
Trusted Cutoff329.60
Domain Trusted Cutoff329.60
Noise Cutoff326.65
Domain Noise Cutoff326.65
Isology Typeequivalog
HMM Length290
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0006310: DNA recombination biological_process
GO:0009009: site-specific recombinase activity molecular_function
AuthorHaft DH
Entry DateJun 16 2004 3:17PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerD, one of two closely related chromosomal proteins along with XerC (TIGR02224). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and with homologs of XerD on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerD, as some apparent XerD examples score below the trusted and noise cutoff scores. XerC and XerD interact with cell division protein FtsK.
References DR HAMAP; MF_01807; 64 of 67