HMM Summary Page: TIGR02197

FunctionADP-glyceromanno-heptose 6-epimerase
Gene SymbolrfaD
Trusted Cutoff274.60
Domain Trusted Cutoff274.60
Noise Cutoff199.70
Domain Noise Cutoff199.70
Isology Typeequivalog
EC Number5.1.3.20
HMM Length316
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Gene Ontology TermGO:0008712: ADP-glyceromanno-heptose 6-epimerase activity molecular_function
GO:0009244: lipopolysaccharide core region biosynthetic process biological_process
AuthorHaft DH
Entry DateMay 17 2004 11:47AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of examples of ADP-L-glycero-D-mannoheptose-6-epimerase, an enzyme involved in biosynthesis of the inner core of lipopolysaccharide (LPS) for Gram-negative bacteria. This enzyme is homologous to UDP-glucose 4-epimerase (TIGR01179) and belongs to the NAD dependent epimerase/dehydratase family (PF01370).
ReferencesDR PFAM; PF01370; NAD dependent epimerase/dehydratase family DR HAMAP; MF_01601; 105 of 107
Genome PropertyGenProp0203: LPS inner core biosynthesis, ketodeoxyoctonate and heptose type (HMM)