| Accession | TIGR02197 |
| Name | heptose_epim |
| Function | ADP-glyceromanno-heptose 6-epimerase |
| Gene Symbol | rfaD |
| Trusted Cutoff | 274.60 |
| Domain Trusted Cutoff | 274.60 |
| Noise Cutoff | 199.70 |
| Domain Noise Cutoff | 199.70 |
| Isology Type | equivalog |
| EC Number | 5.1.3.20 |
| HMM Length | 316 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
| Gene Ontology Term | GO:0008712: ADP-glyceromanno-heptose 6-epimerase activity molecular_function |
| | GO:0009244: lipopolysaccharide core region biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | May 17 2004 11:47AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family consists of examples of ADP-L-glycero-D-mannoheptose-6-epimerase, an enzyme involved in biosynthesis of the inner core of lipopolysaccharide (LPS) for Gram-negative bacteria. This enzyme is homologous to UDP-glucose 4-epimerase (TIGR01179) and belongs to the NAD dependent epimerase/dehydratase family (PF01370). |
| References | DR PFAM; PF01370; NAD dependent epimerase/dehydratase family
DR HAMAP; MF_01601; 105 of 107 |
| Genome Property | GenProp0203: LPS inner core biosynthesis, ketodeoxyoctonate and heptose type (HMM) |
