| Accession | TIGR02194 |
| Name | GlrX_NrdH |
| Function | glutaredoxin-like protein NrdH |
| Gene Symbol | nrdH |
| Trusted Cutoff | 85.75 |
| Domain Trusted Cutoff | 85.75 |
| Noise Cutoff | 72.05 |
| Domain Noise Cutoff | 72.05 |
| Isology Type | subfamily |
| HMM Length | 72 |
| Author | Selengut J |
| Entry Date | May 17 2004 10:48AM |
| Last Modified | Mar 1 2011 11:50AM |
| Comment | NrdH-redoxin is a representative of a class of small redox proteins that contain a conserved CXXC motif and are characterized by a glutaredoxin-like amino acid sequence and thioredoxin-like activity profile. Unlike other the glutaredoxins to which it is most closely related, NrdH aparrently does not interact with glutathione/glutathione reductase, but rather with thioredoxin reductase to catalyze the reduction of ribonucleotide reductase. |
| References | RN [1]
RM PMID: 11441020
RT Structural basis for the thioredoxin-like activity profile of the glutaredoxin-like NrdH-redoxin from Escherichia coli.
RA Stehr M, Schneider G, Aslund F, Holmgren A, Lindqvist Y.
RL J Biol Chem. 2001 Sep 21;276(38):35836-41. Epub 2001 Jul 05. |
| Genome Property | GenProp0289: class I (aerobic) ribonucleotide reductase (HMM) |
