HMM Summary Page: TIGR02193

Functionlipopolysaccharide heptosyltransferase I
Gene SymbolwaaC
Trusted Cutoff185.30
Domain Trusted Cutoff185.30
Noise Cutoff144.00
Domain Noise Cutoff144.00
Isology Typeequivalog
EC Number2.4.-.-
HMM Length320
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Gene Ontology TermGO:0008920: lipopolysaccharide heptosyltransferase activity molecular_function
GO:0009244: lipopolysaccharide core region biosynthetic process biological_process
AuthorHaft DH
Entry DateMay 17 2004 10:34AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of examples of ADP-heptose:LPS heptosyltransferase I, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria.
ReferencesDR PFAM; PF01075 RN [1] RM 9831648 RT Cloning, sequencing, and characterization of the lipopolysaccharide biosynthetic enzyme heptosyltransferase I gene (waaC) from Campylobacter jejuni and Campylobacter coli. RA Klena JD, Gray SA, Konkel ME. RL Gene. 1998 Nov 19;222(2):177-85.
Genome PropertyGenProp0203: LPS inner core biosynthesis, ketodeoxyoctonate and heptose type (HMM)