HMM Summary Page: TIGR02179

Function2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family
Trusted Cutoff60.05
Domain Trusted Cutoff60.05
Noise Cutoff55.55
Domain Noise Cutoff55.55
Isology Typesubfamily
HMM Length78
AuthorHaft DH
Entry DateMay 6 2004 12:45PM
Last ModifiedFeb 14 2011 3:27PM
CommentA number of anaerobic and microaerophilic species lack pyruvate dehydrogenase and have instead a four subunit, oxygen-sensitive pyruvate oxidoreductase, with either ferredoxins or flavodoxins used as the acceptor. Several related four-subunit enzymes may exist in the same species. This model describes a subfamily of delta subunits, representing mostly pyruvate, 2-ketoisovalerate, and 2-oxoglutarate specific enzymes. The delta subunit is the smallest and resembles ferredoxins.