Accession | TIGR02175 |
Name | PorC_KorC |
Function | 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family |
Trusted Cutoff | 81.10 |
Domain Trusted Cutoff | 81.10 |
Noise Cutoff | 72.40 |
Domain Noise Cutoff | 72.40 |
Isology Type | subfamily |
HMM Length | 177 |
Author | Haft DH |
Entry Date | May 5 2004 3:48PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | A number of anaerobic and microaerophilic species lack pyruvate dehydrogenase and have instead a four subunit, oxygen-sensitive pyruvate oxidoreductase, with either ferredoxins or flavodoxins (H. pylori) used as the acceptor.
Several related four-subunit enzymes may exist in the same species. This model describes the gamma subunit. In Pyrococcus furious, enzymes active on pyruvate and 2-ketoisovalerate share a common gamma subunit. |
References | RM 8550425
RT Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima.
RA Kletzin A, Adams MW.
RL J Bacteriol. 1996 Jan;178(1):248-57.
DR PFAM; PF01558 |