HMM Summary Page: TIGR02153

Functionglutamyl-tRNA(Gln) amidotransferase, subunit D
Gene SymbolgatD
Trusted Cutoff324.00
Domain Trusted Cutoff324.00
Noise Cutoff258.35
Domain Noise Cutoff258.35
Isology Typeequivalog
EC Number6.3.5.-
HMM Length405
Mainrole CategoryProtein synthesis
Subrole CategorytRNA aminoacylation
Gene Ontology TermGO:0006424: glutamyl-tRNA aminoacylation biological_process
GO:0050567: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity molecular_function
AuthorHaft DH
Entry DateMar 25 2004 12:25PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis peptide is found only in the Archaea. It is part of a heterodimer, with GatE (TIGR00134), that acts as an amidotransferase on misacylated Glu-tRNA(Gln) to produce Gln-tRNA(Gln). The analogous amidotransferase found in bacteria is the GatABC system, although GatABC homologs in the Archaea appear to act instead on Asp-tRNA(Asn).
ReferencesRM 10993083 RT Domain-specific recruitment of amide amino acids for protein synthesis. RA Tumbula DL, Becker HD, Chang WZ, Soll D. RL Nature. 2000 Sep 7;407(6800):106-10. DR HAMAP; MF_00586; 29 of 29
Genome PropertyGenProp0258: tRNA aminoacylation (HMM)
GenProp0831: archaeal core gene set, exactly 1 per genome (HMM)