HMM Summary Page: TIGR02152

Gene SymbolrbsK
Trusted Cutoff299.65
Domain Trusted Cutoff299.65
Noise Cutoff172.40
Domain Noise Cutoff172.40
Isology Typeequivalog
EC Number2.7.1.15
HMM Length298
Mainrole CategoryEnergy metabolism
Subrole CategorySugars
Gene Ontology TermGO:0004747: ribokinase activity molecular_function
GO:0019303: D-ribose catabolic process biological_process
AuthorHaft DH
Entry DateMar 16 2004 9:43AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (PF00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not.
ReferencesDR EXPERIMENTAL; SP|P32143; Escherichia coli DR EXPERIMENTAL; SP|P36945; Bacillus subtilis DR EXPERIMENTAL; GP|4959404; Lactobacillus sakei