HMM Summary Page: TIGR02151

Functionisopentenyl-diphosphate delta-isomerase, type 2
Gene Symbolfni
Trusted Cutoff281.30
Domain Trusted Cutoff281.30
Noise Cutoff153.70
Domain Noise Cutoff153.70
Isology Typeequivalog
EC Number5.3.3.2
HMM Length338
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0004452: isopentenyl-diphosphate delta-isomerase activity molecular_function
GO:0008299: isoprenoid biosynthetic process biological_process
AuthorHaft DH
Entry DateMar 15 2004 10:47PM
Last ModifiedFeb 14 2011 3:27PM
CommentIsopentenyl-diphosphate delta-isomerase (IPP isomerase) interconverts isopentenyl diphosphate and dimethylallyl diphosphate. This HMM represents the type 2 enzyme. FMN, NADPH, and Mg2+ are required by this form, which lacks homology to the type 1 enzyme (TIGR02150). IPP is precursor to many compounds, including enzyme cofactors, sterols, and isoprenoids.
ReferencesDR EXPERIMENTAL; SP|P58052; Staphylococcus aureus DR EXPERIMENTAL; SP|Q9KWG2; Streptomyces sp. CL190 DR EXPERIMENTAL; SP|O26154; Methanobacterium thermoautotrophicum RM 14745175 RT Bacillus subtilis ypgA gene is fni, a nonessential gene encoding type 2 isopentenyl diphosphate isomerase. RA Takagi M, Kaneda K, Shimizu T, Hayakawa Y, Seto H, Kuzuyama T. RL Biosci Biotechnol Biochem. 2004 Jan;68(1):132-7. DR HAMAP; MF_00354; 127 of 127
Genome PropertyGenProp0758: lycopene biosynthesis from IPP (HMM)