HMM Summary Page: TIGR02121

Functionsodium/proline symporter
Gene SymbolputP
Trusted Cutoff515.50
Domain Trusted Cutoff515.50
Noise Cutoff260.75
Domain Noise Cutoff260.75
Isology Typeequivalog
HMM Length488
Mainrole CategoryTransport and binding proteins
Subrole CategoryAmino acids, peptides and amines
Gene Ontology TermGO:0005298: proline:sodium symporter activity molecular_function
GO:0015824: proline transport biological_process
GO:0016020: membrane cellular_component
AuthorHaft DH
Entry DateFeb 10 2004 4:23PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores.