HMM Summary Page: TIGR02120

Functiontype II secretion system protein F
Gene SymbolgspF
Trusted Cutoff424.00
Domain Trusted Cutoff424.00
Noise Cutoff395.55
Domain Noise Cutoff395.55
Isology Typeequivalog
HMM Length401
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0008565: protein transporter activity molecular_function
GO:0015627: type II protein secretion system complex cellular_component
GO:0015628: protein secretion by the type II secretion system biological_process
AuthorSelengut J
Entry DateFeb 10 2004 9:44AM
Last ModifiedFeb 17 2012 10:32AM
CommentThis membrane protein is a component of the terminal branch complex of the general secretion pathway (GSP), also known as the"Type II" secretion pathway. The GSP transports proteins (generally virulence-associated cell wall hydrolases) across the outer membrase of the bacterial cell. Transport across the inner membrane is often, but not exclusively handled by the Sec system. This model was constructed from the broader subfamily model, PF00482 which includes components of pilin complexes (PilC) as well as other related genes. GspF is nearly always gene clustered with other GSP subunits. Some genes from Xylella and Xanthomonas strains score below the trusted cutoff due to excessive divergence from the family such that a sequence from Deinococcus which does not appear to be GspF scores higher.
Genome PropertyGenProp0053: type II secretion (HMM)