HMM Summary Page: TIGR02105

Functiontype III secretion apparatus needle protein
Gene SymboleprI
Trusted Cutoff41.70
Domain Trusted Cutoff41.70
Noise Cutoff28.25
Domain Noise Cutoff28.25
Isology Typeequivalog
HMM Length72
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0030254: protein secretion by the type III secretion system biological_process
AuthorHaft DH
Entry DateJan 20 2004 5:26PM
Last ModifiedFeb 14 2011 3:27PM
CommentType III secretion systems translocate proteins, usually virulence factors, out across both inner and outer membranes of certain Gram-negative bacteria and further across the plasma membrane and into the cytoplasm of the host cell. This protein, termed YscF in Yersinia, and EscF, PscF, EprI, etc. in other systems, forms the needle of the injection apparatus.
ReferencesRM 14580388 RT Genetic analysis of the formation of the Ysc-Yop translocation pore in macrophages by Yersinia enterocolitica: role of LcrV, YscF and YopN. RA Marenne MN, Journet L, Mota LJ, Cornelis GR. RL Microb Pathog. 2003 Dec; 35(6): 243-58. DR EXPERIMENTAL; SP|Q01247; Yersinia enterocolitica plasmid pYV
Genome PropertyGenProp0052: type III secretion (HMM)