HMM Summary Page: TIGR02103

Functionalpha-1,6-glucosidases, pullulanase-type
Gene SymbolpulA
Trusted Cutoff697.60
Domain Trusted Cutoff697.60
Noise Cutoff384.05
Domain Noise Cutoff384.05
Isology Typesubfamily_domain
EC Number3.2.1.41
HMM Length900
Mainrole CategoryEnergy metabolism
Subrole CategoryBiosynthesis and degradation of polysaccharides
Gene Ontology TermGO:0005983: starch catabolic process biological_process
GO:0051060: pullulanase activity molecular_function
GO:0051678: pullulan catabolic process biological_process
AuthorHaft DH
Entry DateJan 20 2004 3:36PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family include secreted (or membrane-anchored) pullulanases of Gram-negative bacteria and pullulanase-type starch debranching enzymes of plants. Both enzymes hydrolyze alpha-1,6 glycosidic linkages. Pullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave alpha-1,6 linkages in pullulan and release maltotriose are called pullulanases although pullulan itself may not be the natural substrate. This family is closely homologous to, but architecturally different from, the Gram-positive pullulanases of Gram-positive bacteria (TIGR02102).